“Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia … Its goal is to allow the public “to know how the NIH spends their tax dollars,” but it has been little used. Schizophrenia Bulletin. (5) Invited comments or hypotheses( Less than 1000 words). People with schizophrenia should protect their mental health during the COVID-19 pandemic. It’s not easy to determine the causes, because the symptoms can vary from one person to another. Laura Stertz, Jessica Di Re, Guangsheng Pei, Gabriel R. Fries, Emily Mendez, Shenglan Li, Laura Smith-Callahan, Henriette Raventos, Jerricho Tipo, Rohan Cherukuru, Zhongming Zhao, Ying Liu, Peilin Jia, Fernanda Laezza, Consuelo Walss-Bass. University of Texas Health Science Center at Houston. (2020, December 21). "Mental health research has lagged behind because we don't know what is happening biologically. A multidisciplinary approach is essential to help individuals with this health condition, and psychological … Through human-induced pluripotent stem cell (hiPSC) technology, the blood cells were reprogrammed into stem cells, which were then directed to become brain neurons. Those neurons could be studied in a virtual biopsy and compared to neurons engineered from individuals who did not have schizophrenia, but came from the same family from a homogenous population in the Central Valley of Costa Rica. Context-dependent language of auditory hallucinations in an adolescent learning a second language: A case study applying the inner speech model, Consistency checks to improve measurement with the Personal and Social Performance Scale (PSP), Can't get you out of my head: Persistence and remission of psychotic experiences in adolescents and its association with self-injury and suicide attempts, Reduction of GABA subunit theta-containing cortical neurons in schizophrenia, Download the ‘Understanding the Publishing Process’ PDF, Check the status of your submitted manuscript in the. The specific symptoms that have been felt to characterize schizophrenia have varied widely over time and across cultures, as has the diagnostic and prognostic importance placed on these symptoms. (7) Schizophrenia … The journal publishes novel papers that really contribute to understanding the biology and treatment of schizophrenic disorders; Schizophrenia Research brings together biological, clinical and psychological research in order to stimulate the synthesis of findings from all disciplines involved in improving patient outcomes in schizophrenia. Schizophrenia Research is a Subscription-based (non-OA) Journal. Walss-Bass said identifying patients with specific biological pathway markers could identify them as the best candidates for medications, creating the personal pharmacology that is needed to treat psychiatric disorders. (4) Special solicited research and/or reviews. A lot of research has attempted to uncover the causes of schizophrenia. Distinguished Professor Xu-Feng Huang is a National Health and Medical Research Council (NHMRC) Leadership Fellow who received a 2019 NHMRC Investigator grant for schizophrenia research. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. In 2008 the National Institutes of Health established the Research, Condition and Disease Categorization Database (RCDC) that reports the amount spent by NIH institutes for each disease. Schizophrenia is a serious mental illness characterized by incoherent or illogical thoughts, bizarre behavior and speech, and delusions or hallucinations, such as hearing voices. New Device Detects Which Hand Gesture You Want to Make, Key Advance for Printing Circuitry on Wearable Fabrics, Luminescent Wood Could Light Up Homes of the Future, Research Lays Groundwork for Ultra-Thin, Energy Efficient Photodetector on Glass. Among the differentially expressed genes the researchers saw in the virtual biopsies were five that have previously been identified as schizophrenia candidate genes by genome-wide association studies. University of Texas Health Science Center at Houston. For schizophrenia, a dose range of 37–148 mg daily is recommended, with a lower dose range of 18.5–120 mg daily, recommended for bipolar depression (lurasidone at lower doses of 20–60 mg daily has been shown to be as clinically efficacious in bipolar depression, as at the higher dose range of 80–100 mg/day). Or view hourly updated newsfeeds in your RSS reader: Keep up to date with the latest news from ScienceDaily via social networks: Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. (7) Schizophrenia meeting reviews; solicited and/or submitted. Note: Content may be edited for style and length. Treatment of Adolescent and Child Schizophrenia Schizophrenia is much less common in children Read more... Posted by Megan at 09:24 PM | Comments (0) September 30, 2005 . The study was supported by an award from The University of Texas System (UT BRAIN), and a Brain and Behavior Research Foundation Young Investigator Award to Stertz. Schizophrenia is a complex, heterogeneous disorder, with highly variable treatment outcomes, and relatively little is known about what is important to patients.